Individual
DC projects

All projects

Research project

Development of Therapeutic Antibodies for Treating Acute Myeloid Leukemia

Rationale and Objectives

The primary objective of this project is to develop therapeutic antibodies for the treatment of AML.

See more

Therefore, the specific objectives of this project are:

  1. Generating high-affinity antibodies that are specific to AML and capable of restoring immune surveillance against leukemia cells by performing single-cell sequencing of rabbit B-cells using the 10x Genomics platform.
  2. Testing the binding affinity and specificity of the generated antibodies against AML cells.
  3. Translating these results into effective treatment options for AML patients by enhancing immune responses with improved specificity and efficacy.

See less

Estimated gross salary

38,000€/year

This project may be adapted to the evolving needs of the host laboratory while remaining within hemato-oncology research. The DC will undertake one or more secondments with a total duration of at least three months and up to one year. These secondments may take place within or outside the DN, preferably in international and intersectoral settings.